Bioinformatics Specialist

A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position. Please also provide contact information of two references for consideration.

Job Summary

Applications are invited for a Research Lab Specialist position in the Laboratory of Spatial Systems Biology of Dr. Yang Xiao in the Department of Pathology at the University of Michigan Medical School (https://www.pathology.med.umich.edu/faculty/yangxa). This is a highly interdisciplinary lab focused on both genetic and epigenetic changes in traumatic brain injury. We are an innovative, friendly, energetic, and supportive group dedicated to healthy research environment. In this role, the candidate will work as a bioinformatics specialist examining the spatial transcriptomic and epigenetic changes in brain injury and post-injury remodeling. The candidate will be responsible for sequencing data analysis, data management, codes maintenance and perform routine laboratory computational procedures in one or more areas of work under the supervision of the principal investigator.

Mission Statement

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Why Join Michigan Medicine?

Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world’s most distinguished academic health systems. In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.

What Benefits can you Look Forward to?

• Excellent medical, dental and vision coverage effective on your very first day
• 2:1 Match on retirement savings

Responsibilities*

• Scientific data collection and analysis
• Algorithm development, codes maintenance and data management
• Assistance in preparation of figures, reports and manuscripts
• Supervision and onboarding computational training of junior lab members
• Follow and maintain laboratory protocols and procedures
• Assist the principal investigator with lab maintenance

Required Qualifications*

• Bachelor’s degree in Bioinformatics, Bioengineering, Biomedical Computing, Biostatistics, Data Science, Computer Science or related field
• At least 1 year of research experience in related field
• Research experience of statistical methods commonly used in single-cell and spatial omics, such as Seurat and Scanpy
• Familiar in programming of common statistical languages such as R and Python
• Familiar with Linux OS, Virtual Environment working and batch scripting.
• Familiar with epigenome sequencing analysis such as ArchR and SnapATAC2 for sequencing alignment, peak calling, and motif score calculations
• Knowledge of Machine learning/Deep learning is needed.
• High-level of personal initiative; ability to work independently as well as collaborate in teams
• Strong organizational skills and attention to detail
• Strong written and oral communication skills; must be able to communicate clearly

Desired Qualifications*

• Research experience in single-cell and spatial omics related to brain
• Experience with Spatial ATAC-Seq and Spatial CUT&TAG Seq
• Experience with multiplexed imaging data processing and neighborhood analysis
• Experience with NCBI data deposition and GitHub codes maintenance
• Organization of workshops on programming languages and omics analysis
• Master’s degree in Bioinformatics, Bioengineering, Biomedical Computing, Biostatistics, Data Science, Computer Science or related field

Modes of Work

Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the .

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline

Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

U-M EEO Statement

The University of Michigan is an equal employment opportunity employer.

Source ⇲